Aistriú cothrománach géine

Ón Vicipéid, an chiclipéid shaor.
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Léiríonn 'Crann na beatha' seo aistriú ingearach agus cothrománach géine.

Is éard is aistriú cothrománach géine (ACG) nó aistriú cliathánach géine [1][2] ná an ghluaiseacht d'ábhar géiniteach idir orgánaigh aoncheallacha  agus/nó ilcheallacha, cé is moite de tharchur ADN ó thuismitheoir chuig a shliocht.[3] Toisc thábhachtach is ea ACG in éabhlóid go leor orgánach.[4][5]

Tá ACG ina phríomh-mheicníocht i leathnú frithsheasmhacht in aghaidh antaibheathach i mbaictéir,[6][7][8][9] agus glacann sé ról tábhachtach in éabhlóid na mbaictéar gur féidir leo comhdhúile nuálacha, a leithéid agus lotnaidicídí shaorga a dhíghrádú[10] agus in éabhlóid, i  gcothabháil, agus i dtarchur nimhneachta.[11] Is minic a bhíonn baictéarafagaigh mheasartha agus plasmids páirteach ann.[12][13][14]  Is féidir le géinte, atá freagrach as frithsheasmhacht in aghaidh antaibheathach i speiceas baictéarach amháin, aistriú chuig speicieas eile trí mheicníochtaí éagsúla, ar nós F pileas, agus ina dhiaidh sin faighteora na ngéinte frithsheasmhacht a armáil in aghaidh antaibheathach, a bhfuil ag éirí dúshlánach ó thaobh na sláinte de. Samhlaítear freisin go gcuireann ACG chun cinn cothabháil saol uilíoch na bithcheimice agus, ina dhiaidh sin, uilíocht an chóid ghéinitigh.[15] Bhí go leor machnaimh faoin ghéineolaíocht dírithe ar an aistriú cothrománach, ach níl  an tábhacht a bhaineann le haistriú ingearach  géine i measc orgánach aoncheallach ach ina thús.[16][17]

Is féidir glacadh le seachadadh géinte mar  aistriú saorga géine, agus is saghas d' innealtóireacht ghéiniteach í.

Foinsí agus nótaí[cuir in eagar | athraigh foinse]

  1. Ochman, H., Lawrence, J. G., & Groisman, E. A. (May 2000). "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Nature 405 (6784): 299–304. doi:10.1038/35012500. PMID 10830951. CS1 maint: Multiple names: authors list (link)Dunning Hotopp, J. C. (April 2011). "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Trends in Genetics 27 (4): 157–163. doi:10.1016/j.tig.2011.01.005. PMID 21334091. PMC:3068243. 
  2. Robinson, K. M., Sieber, K. B., & Dunning Hotopp, J. C. (October 2013). "A review of bacteria-animal lateral gene transfer may inform our understanding of diseases like cancer". PLoS Genet 9 (10): e1003877. doi:10.1371/journal.pgen.1003877. PMID 24146634. PMC:3798261. CS1 maint: Multiple names: authors list (link)
  3. Keeling, P. J., & Palmer, J.D. (2008). "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Nature Reviews Genetics 9 (8): 605–618. doi:10.1038/nrg2386. PMID 18591983. CS1 maint: Multiple names: authors list (link)
  4. Gyles, C. (March 2014). "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Veterinary Pathology 51 (2): 328–340. doi:10.1177/0300985813511131. PMID 24318976. 
  5. "Speciation through the looking-glass" (2017). Biological Journal of the Linnean Society 120 (2): 480–488. doi:10.1111/bij.12872. 
  6. OECD, Safety Assessment of Transgenic Organisms, Volume 4: OECD Consensus Documents, 2010, pp.171-174
  7. "In situ transfer of antibiotic resistance genes from transgenic (transplastomic) tobacco plants to bacteria" (July 2002). Appl. Environ. Microbiol. 68 (7): 3345–51. doi:10.1128/aem.68.7.3345-3351.2002. PMID 12089013. PMC:126776. 
  8. "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}" (2001). Annu. Rev. Microbiol. 55 (1): 709–42. doi:10.1146/annurev.micro.55.1.709. PMID 11544372. PMC:4781227. 
  9. Nielsen KM (1998). "{{{title}}}". APMIS Suppl. 84: 77–84. PMID 9850687. 
  10. "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}" (October 1998). Appl. Environ. Microbiol. 64 (10): 4089–92. PMID 9758850. PMC:106609. 
  11. "Citation is missing a title. Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}" (December 2012). Frontiers in Cellular and Infection Microbiology 2. doi:10.3389/fcimb.2012.00161. PMID 23248780. 
  12. "Transfer of broad-host-range antibiotic resistance plasmids in soil microcosms" (1994). Curr. Microbiol. 28 (4): 209–215. doi:10.1007/BF01575963. 
  13. "Efficient transfer of antibiotic resistance plasmids by transduction within methicillin-resistant Staphylococcus aureus USA300 clone" (2012). FEMS Microbiol. Lett. 332 (2): 146–152. doi:10.1111/j.1574-6968.2012.02589.x. PMID 22553940. 
  14. "Molecular characterization of a new efficiently transducing bacteriophage identified in meticillin-resistant Staphylococcus aureus" (2016). Journal of General Virology 97 (1): 258–268. doi:10.1099/jgv.0.000329. PMID 26537974. 
  15. "On universal coding events in protein biogenesis" (2017). Biosystems. doi:10.1016/j.biosystems.2017.10.004. 
  16. "Horizontal gene transfer in microbes much more frequent than previously thought".
  17. "To Share and Share Alike: Bacteria swap genes with their neighbors more frequently than researchers have realized".